MEDICINAL CHEMISTRY & BIOLOGY

Future Challenges and Solutions with Advanced In-Vitro Assay Systems – A Look at Phenotypic and Biomarker Assays —Quench Bio Building translational confidence through deep phenotyping & multi-omics to influence pre-clinical safety & drug design —AstraZeneca Selection of the optimal modality for a given biological target – how to optimize drugability —AstraZeneca Strategies for Monitoring the Quality of Outsourced Work – The Vulnerabilities Involved and How to Identify New Strategic Partnerships (TBC) —Sorrento Therapeutics      

Kinase Inhibitor Drug Discovery for Cancer: Current approaches and future outlooks – BioDuro-Sundia How do we improve HTS to increase the supply of Hits that successfully transition to Leads? – WuXi AppTec, Research Service Division Data Driven Drug Discovery Strategies – PerkinElmer Target Discovery, Identification and Validation – WuXi AppTec Solving the R&D efficiency conundrum within drug discovery – Bit.Bio Strategy and Implementation for New Modalities in Drug Discovery: PROTAC, ASO and RNAi – WuXi AppTec

DEL technology: the past, present and future • Technical advancement in DEL technology • New modalities of DEL technology • How to make DEL more accessible and it’s data more re-usable —WuXi AppTec

Digital Transformation of Drug Discovery: How do you measure transformation? – Bayer Evolution of Integrated Drug Discovery – Glycologix Target Validation – How Do We Get Closer to Human Disease? – LifeArc Vetting targets before betting all the chips: druggability assessment and prioritization – Cedilla Therapeutics Considerations in the design & synthesis of new modalities – Amphilix New Tools and Technologies – Can 3D Culture, HiPSC and Organ-on-chip Technologies Help to Bridge the Translational Medicine Gap? – EnClear Therapies Implementing AI for Decision Making in Drug Discovery: How Can Applying AI in DMPK Impact Drug Discovery? – AstraZeneca Beginning with the end in mind: outlining the essential and critical decisions towards better collaboration – Amcure GmbH  

Expediting the Drug Discovery Process Through Chemistry and Biology: Leveraging AI in Hit Finding and Lead Optimization — Agios Pharmaceuticals Strategies to discover novel drug targets — AstraZeneca Some insights about predictive toxicity —AB Science Translatability – from in vitro to in vivo, preclinic to clinic, bench to bedside — PTC Therapeutics Translational PK/PD to build confidence and facilitate decision making in discovery and early development — Roche Recent progress in TPD: solving challenges and issues facing targeted protein degradation— Proteovant Therapeutics Building Strong Collaborations with Therapeutic Area Partners— Sanofi