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Abizer |
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Harianawala |
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Vice President, CMC & Technical Operations |
Alkeus Pharmaceuticals, Inc. |
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Art |
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Faulkner |
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Vice President, Regulatory CMC |
TG Therapeutics, Inc. |
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Session – Strategies to manage differing country-specific requirements for submissions
Art Faulkner has worked in the pharmaceutical industry for over 30 years, with more than 20 years experience in regulatory CMC. He is currently the head of regulatory CMC at TG Therapeutics in New York. He has also worked at Edge Therapeutics, Pfizer and worked at Merck He has global experience in Regulatory CMC for initial registrations and post approval changes. He attended University of Scranton (B.S), Bucknell University (M.S.) and Rutgers University (graduate coursework). |
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Ganfeng |
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Cao |
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Vice President and Head of Process Chemistry, CMC |
Prelude Therapeutics |
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George |
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Wu |
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Vice President, CMC |
Enanta Pharmaceuticals |
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Gopi |
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Vudathala |
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Global Head, Regulatory Affairs CMC |
Incyte Corporation |
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Dr. Vudathala, Ph.D., is currently Global Head, RA CMC at Incyte Corporation. He was Formerly Executive Director of RA CMC at Intarcia Therapeutics, Head of Quality Advocacy at GSK Vaccines and Global Head of Regulatory CMC at Novartis Vaccines. He was also Associate Vice President of Regulatory Affairs CMC at Sanofi-Aventis. He has extensive experience in CMC regulatory strategy for Global Development and Life-Cycle Management Projects and contributed to over 30 NDA and BLA approvals and 60 INDs. Dr. Vudathala has had numerous interactions with global regulators on project related CMC matters as well as on key ICH initiatives. He has published extensively on drug development and regulatory CMC topics. He was on the Regulatory and Quality Advisory Board at the Parenteral Drug Association and a member of the PDA core team on ICHQ12/ Post Approval Changes. He was also previously Vice Chair of the Technical Development and Operations Committee at PhRMA and an active member of the PhRMA CTD Quality Task Force, Genotoxic Impurities Task Force, and a working group member of the FDA Subcommittee for Pharmaceutical Sciences on Process Analytical Technologies and Quality-by-Design. He was also the Chair of the Regulatory Sciences Section of AAPS. Dr. Vudathala is a well-recognized expert on Regulatory CMC and Quality matters and has made several presentations at AAPS, PDA, IIR, Barnett & Proventa International workshops and conferences on CMC, Regulatory, CTD, Drug Device Combination Products and Genotoxic Impurities topics. Dr. Vudathala graduated from the University of Alberta with a Ph.D. in Pharmaceutics and held positions with the Health Protection Branch, Canada, and Procter & Gamble Pharmaceuticals |
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Ian |
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O’Reilly |
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Vice President, Quality |
Tessera Therapeutics |
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Jamie |
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Gillette |
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Vice President, Head of Regulatory |
Cullinan Therapeutics |
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Jamie Gillette is Vice President, Head of Regulatory Affairs at Cullinan Oncology of Cambridge, Massachusetts. She is responsible for Regulatory strategy and operations for all Cullinan pipeline products.
Jamie possesses 20+ years of global drug development, clinical trials, and Regulatory experience and has held leadership positions at multiple organizations in the biopharmaceutical industry. She has experience throughout the product life cycle, from INDs through Marketing Applications and across multiple therapeutic areas including oncology, inflammation, and vaccines.
As a community leader, Jamie has been an instructor and avid student in Budo Taijutsu for over 10 years. She is also Vice President of the Howard County Veterans Foundation whose mission is to develop and construct the Howard County Veterans Monument in Columbia, Maryland. |
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Kelly |
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Neelon |
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Vice President, CMC and Technical Operations |
Vigil Neuroscience |
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Kelly Neelon is a product development professional with over 15 years of industry experience in biotech and pharma. Technical expertise in analytical development, formulation development, drug product development and manufacturing across the program lifecycle. |
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Kristen |
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Manion |
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Vice President, Head of Regulatory Affairs, Quality and Manufacturing |
Paratek Pharmaceuticals |
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Mahesh |
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Padval |
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Chief Pharmaceutical Development Officer |
Relay Therapeutics |
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As Chief Pharmaceutical Development Officer, Mahesh Padval guides transition of the Company’s late research assets into development and oversees pharmaceutical development activities to support regulatory filings and product commercialization. Mahesh brings to Relay Therapeutics nearly 30 years of product development experience in the pharmaceutical industry. Prior to joining Relay Therapeutics, Mahesh was vice president of pharmaceutical sciences and product development at Verastem, Inc. There, he was responsible for preclinical development, CMC and clinical pharmacology activities in support of the company’s development programs through non-clinical, clinical development and regulatory filings, including the approval and commercial launch of COPIKTRA TM. Prior to Verastem, Mahesh held roles of increasing responsibility at Zalicus, Inc., culminating in his role as vice president of preclinical development and formulations. He also held roles at Charles River Discovery and Development Services and Genzyme Transgenics Corporation. Mahesh holds a Ph.D. and M.S. in industrial pharmacy from Massachusetts College of Pharmacy, CSS in administration and management from Harvard University and a Bachelor of Pharmacy from the University of Bombay, India. |
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Niels |
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Svenstrup |
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Senior Vice President, Chemistry & Manufacturing |
PepGen |
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Niels Svenstrup has over 20 years of experience in the pharma and biotech industry across various leadership roles in chemistry and manufacturing. He recently founded Creative Molecular Consulting, where he is advising early-stage companies on navigating the transition from discovery to preclinical and clinical development from a CMC, regulatory, and business perspective. Niels has a master’s in cell biology and chemistry, a Ph.D. in organic chemistry, and did his postdoctoral training at The Scripps Research Institute in La Jolla, CA. He joined the pharmaceutical industry as a laboratory leader in medicinal chemistry at Bayer Pharma in Germany in 2000. He later went on to become Head of Department, Medicinal Chemistry at H. Lundbeck’s Neuroscience Drug Discovery Center in Copenhagen, Denmark, before joining Ascendis Pharma as Director of CMC and leader of the team that invented and developed TransCon PTH (now YorviPath), an approved drug in the EU and US for the treatment of hypoparathyroidism. Niels moved to the U.S. in 2017 to take on the role of Senior Vice President, Development at Cydan, a rare disease accelerator located in Cambridge, MA. Most recently, Niels was SVP of Chemistry and Manufacturing at PepGen Inc. from 2021 to 2025 |
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Pradeep |
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Sharma |
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Global Head, Pharmaceutical & Technical Ops, Small Molecule & Oligonucleotides |
Takeda |
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Pradeep Sharma is an accomplished CMC leader in pharmaceutical industry with experience in CDMOs, Generic drug manufacturing, New Chemical entities (NCEs) including commercial process development, preformulation studies, solid oral dosage development, optimization, managing product life cycle etc. Authored multiple DMFs, INDs, IMPDs, CTAs, NDAs, MAAs, PMDAs, etc. for Global market approvals. Recently led CMC teams for submissions and approvals of multiple NCEs: Ridaforolimus, ponatinib, brigatinib, mobocertinib, maribavir. Presently employed at Takeda Pharmaceuticals Co. Intl. Co. Ltd., Cambridge, MA. |
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Seshu |
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Tyagarajan |
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Chief Technical and Development Officer |
Candel Therapeutics |
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Dr. Seshu Tyagarajan is the Chief Technical and Development Officer at Candel Therapeutics. She has two decades of technical, manufacturing and development experience in Biologics and Cell & Gene therapies. Prior to Candel, she was Global Head, CMC Strategy for CGT at Novartis where she developed the clinical and commercial manufacturing strategy for T-Charge™(CAR-T). She successfully led several BLAs and INDs and was a key contributor to the groundbreaking BLA submission for Kymriah®.
Seshu held roles of increasing responsibility at Merck, Roche, Phyton, Biogen and Lilly. She holds a Ph.D. in Chemical and Biochemical Engineering (Rutgers), and MS in Bioengineering (Purdue).
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Sheila |
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Mathias |
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Chief Scientific Officer |
Virpax Pharmaceuticals, Inc. |
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Dr. Sheila A. Mathias has more than 20 years of leadership experience in the pharmaceutical industry accelerating drug development. She brings extensive global regulatory affairs strategic guidance and clinical development experience having worked across a range of therapeutics areas, including pain management, addiction medicine, and dermatology. This experience has spanned across big pharma, mid-sized, to start-up biotechnology companies. Most recently, she held the position Senior Director Global Regulatory Affairs at Sun Pharma Advanced Research Company. Sheila has held increasing roles of responsibilities, entering the pharmaceutical industry at Merck US Human Health in the position of Medical Science Liaison. Dr. Mathias transitioned into Regulatory Affairs at Aventis Pharmaceuticals and has successfully brought multiple products through regulatory approval.
Dr. Mathas received a B.S in Zoology from Howard University, a PhD in Neurophysiology from Meharry Medical College, an executive MBA from Saint Joseph’s University, and a JD from Northwestern California University School of Law. Since 2018 she has served on the Advisory Board for Tennessee State University Department of Biology |
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Yanhuai |
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(Richard) Ding |
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Head, Purification Process Development, Gene Therapy |
Biogen |
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Vimal |
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Patel |
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Vice President, Head of CMC |
Orum Therapeutics |
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Vimal is currently Vice President, Head of CMC at Orum Therapeutics. Orum is a clinical-stage biotechnology company whose goal is to bring life-changing therapies to patients by combining the power of the emerging field of protein degraders with precision of antibodies to generate a broad portfolio of highly differentiated product candidates.Vimal brings over 20 years of experience in development and manufacturing of mAbs, ADCs, radiopharmaceuticals and small molecules. Previously, Vimal held roles of increasing responsibility with Process Development and Manufacturing Sciences at Daiichi Sankyo, Actinium Pharmaceuticals, Pfizer and Progenics Pharmaceuticals. |