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Aaron |
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Frank |
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Director and Head of Computational Chemistry |
Arrakis Therapeutics |
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Aaron is a Director and Head of Computational Chemistry at Arrakis Therapeutics. Aaron did his Ph.D. at the University of Michigan and then the University of California, Irvine, and developed techniques to integrate NMR and molecular dynamics simulations. After that, he spent two years at Nymirum Inc. (now base4) and another three years as a postdoc at the University of Michigan with Professor Charles Brooks. Before joining Arrakis, Aaron was an Assistant Professor at the University of Michigan, where he led a computational biophysics group focused on modeling the structure and dynamics of RNA. |
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Allen |
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Hopper |
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Vice President, Drug Discovery |
Lucy Therapeutics |
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Allen Hopper received his Ph.D. in Medicinal Chemistry from the Ohio State University in 1993 under the mentorship of Professor D. T. Witiak, followed by a post-doc at the University of Wisconsin. Prior to joining Lucy Therapeutics in 2022, Allen held positions for a variety of Biotech companies including Allelix, Memory, Lundbeck and Sage Therapeutics. Most of his career has been in the area of small molecule CNS drug discovery focused on compound design and building mechanistic links from target engagement to disease relevant biological consequences. Allen authored or co-author approximately 75 patent applications and publications. |
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Andrew |
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L. Roughton, |
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WuXi AppTec Co., Ltd. |
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Andrew Roughton trained in organic chemistry with P. Deslongchamps (Sherbrooke), M. Demuth / K. Schaffner (Max Planck, Mülheim) and S. A. Benner (ETH Zürich). He worked with Pharmacopeia, Inc. (Princeton, NJ) as a medicinal chemist across early Discovery to candidate selection for modulators of several traditional target classes, investigated riboswitch and ubiquitin-proteasome system modulators with Dalton Medicinal Chemistry and then joined Encycle Therapeutics (Toronto, ON) as VP, Discovery & Operations, where he led efforts in proprietary macrocyclization and protein-protein interaction modulators. In August 2019, he joined WuXi AppTec in Boston and is currently Executive Director, Medicinal Chemistry with the Research Chemistry Services/Integrated Program Management team (North America and Europe). |
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Blaise |
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Lippa |
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Chief Scientific Officer |
Morphic Therapeutics |
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Blaise Lippa is the SVP of Molecular Discovery at Morphic Therapeutic, joining the company at its inception and helping to build it through IPO, while advancing integrin small molecule projects towards the clinic. Prior to this, Blaise was a Sr. Director of medicinal chemistry at Cubist Pharmaceuticals, where he led teams that advanced multiple acute care compounds to the clinic, and served on a development team that achieved an NDA. Blaise began his industrial career at Pfizer, working in multiple therapeutic areas, including oncology, antibacterials, and metabolic diseases. A project he initiated and first led was approved in 2019(Daurismo/ Glasdegib) for leukemia. Blaise obtained his B.Sc. degree from the University of Michigan, and his Ph.D. from Stanford. Blaise is an author of over 70 publications and patents. |
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Byron |
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DeLaBarre |
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Former Head of Protein Science & Structural Biology |
PsiThera |
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Carlos |
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Pedraza |
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AVP Biology |
Sai Life Sciences |
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Carlos Pedraza, PhD. is an expert discovery biologist with over 16 years of experience in small molecule drug discovery in the fields of neuroscience, neurodegeneration, neuropsychiatry and neuroimmunology. Carlos’ work in the pharmaceutical industry has been focused in early target identification, scientific evaluation, feasibility assessment and experimental validation of novel, viable targets from concept to portfolio entry, IND and early clinical development. Carlos has extensive experience in collaborative interactions with CROs, academics, scientific groups and other institutions with continuous project management in company-sponsored research. |
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Ching |
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Kim Tye |
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mRNA Director, LNP Platform Development |
Sanofi |
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Kim is a seasoned pharmaceutical professional with two decades of expertise in drug delivery. She has successfully led technical teams in Research and in Development organizations across the pharmaceutical industry, spanning from early discovery to late-stage development. Kim has served in big and mid-size pharma like Pfizer, Bristol-Myers Squibb, Eli Lilly/Elanco, and CSL, where she honed her skills. Presently, she serves as the mRNA Director for LNP Platform Development at Sanofi’s mRNA Center of Excellence. In this role, she remains dedicated to advancing LNP platforms as a delivery system for vaccines and beyond, contributing to the broader realization of the full potential of mRNA medicines. |
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Diane |
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Joseph-McCarthy |
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Executive Director, Bioengineering Technology & Entrepreneurship Center |
Boston University |
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Diane Joseph-McCarthy is the Executive Director of the Bioengineering Technology & Entrepreneurship Center and Professor of the Practice in Biomedical Engineering at Boston University. Prior to that, she was a senior life science executive with over 20 years of drug discovery, development, and leadership experience. She was SVP of Discovery & Early Development at EnBiotix, a bioengineering company focused on respiratory and rare disease. She was an Associate Director at AstraZeneca, where she led a global team and task forces to transform Infection’s early portfolio. At Wyeth, she held positions of increasing responsibility. Diane received her PhD from MIT and was a postdoctoral fellow at Harvard University/Harvard Medical School. |
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Dominic |
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Reynolds |
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Senior Vice President, Head of Drug Discovery |
Remix Therapeutics |
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Dominic has extensive experience in the biotech space and building successful biotech companies. Prior to his current role at Remix therapeutics, recent positions include drug discovery consultancy to two seed-stage companies at Third Rock Ventures and VP, Head of Chemistry at H3 Biomedicine, a company he joined on day one. Prior to that Dominic worked at Forma Therapeutics, where he also joined on the first day, and he started his career at Millennium Pharmaceuticals. He received his PhD in synthetic chemistry from the University of Cambridge and conducted postdoctoral training at Harvard University where he focused on natural product synthesis. |
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Dr. |
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Tamsin Mansley |
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President and Global Head of Application Science |
Optibrium Inc. |
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Tamsin holds a PhD in Organic Chemistry from the University of East Anglia in the UK and pursued Postdoctoral studies in the labs of Prof. Philip Magnus at University of Texas, Austin. She is an experienced drug discovery scientist, having worked as a medicinal chemist at Eli Lilly and UCB Research. Her interests lie in coupling machine learning and artificial intelligence techniques with generative chemistry approaches to explore chemistry space and guide compound design. |
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Ed |
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Olhava |
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Senior Vice President, Preclinical Development |
IFM Therapeutics |
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Over his nearly 20 year career in mid and early-stage biotech, Ed Olhava has invented and progressed multiple compounds through discovery and into clinical development. He has focused on discovering first-in-class small molecule modulators of new biological pathways, closely integrating medicinal chemistry, pharmacology, safety and CMC to enter clinical trials with these novel entities.
Before joining IFM, Ed was a strategic advisor at Third Rock Ventures, where he developed the strategic and operational plans for the drug discovery groups of two Third Rock seed companies, both of which were successfully funded and launched. Prior to Third Rock, he was a founding scientist at Epizyme, joining the company as the first medicinal chemist. He started the medicinal chemistry group and invented Epizyme’s first clinical compound and the first clinical histone methyltransferase inhibitor, EPZ-5676, leading activities from hit finding to filing the Investigational New Drug application. Before joining Epizyme, Ed began his medicinal chemistry career at Millennium Pharmaceuticals, where he co-invented NINLARO, approved in 2015 for the treatment of multiple myeloma, and MLN-4924.
Ed obtained his Ph.D. in synthetic organic chemistry from Harvard University and B.S. in chemistry from Stanford University. He is co-author/inventor on more than 40 papers and patents. |
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Horst |
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Hemmerle |
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Chief Scientific Officer |
Kojin Therapeutics |
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Horst Hemmerle is an experienced drug discovery leader in the pharmaceutical industry. Horst’s illustrious career spans across prominent organizations such as Eli Lilly and Aventis, where he led numerous teams in both biology and chemistry divisions. On his professional journey he joined Novartis in Cambridge as Executive director in 2013. Since that time, he established a global hit-and lead generation organization within Global Discovery Chemistry. Most recently he took on the new role Head of Frontier Chemistry and explores “frontier” areas like AI/ML enabled medicinal chemistry, induced proximity, molecular targeting, drug delivery and bioreactions. Through his visionary guidance, Horst fostered a culture of innovation and achievement within these teams, driving them towards remarkable drug discoveries. |
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Ivan |
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Efremov |
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VP, Head of Medicinal Chemistry |
Nereid Therapeutics |
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Ivan Efremov is a Senior Director, Head of Medicinal Chemistry at Fulcrum Therapeutics. He started his medicinal chemistry career in 2001 when he joined Pfizer after obtaining his PhD with Professor Leo Paquette at The Ohio State University. While at Pfizer, he significantly contributed to multiple projects including delivery of development candidates for CNS, immunology and rare disease indications. He joined Fulcrum Therapeutics in 2017 where he led a chemistry effort culminating in nomination of a development candidate for sickle cell disease. His research interests include structure-based design, fragment-based lead generation, and chemogenomics. He is an author on more than 50 publications and patents. |
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Jacques |
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Dumas |
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Chief Scientific Officer |
Arrakis Therapeutics |
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Jacques Dumas has 30-years experience in drug discovery and development. He is a co-inventor of two marketed drugs in Oncology, Nexavar® and Stivarga®.In January 2020, Jacques joined Arrakis, a biotech company dedicated to the discovery of small molecules targeting RNA. He is currently Chief Scientific Officer (CSO) and oversees all R&D functions. From 2015 to 2019, Jacques was CSO at Tetraphase, focusing on fully synthetic tetracyclines (acquired by La Jolla in 2020) and played a key role in regulatory approvals of eravacycline, a broad-spectrum antibiotic. Before joining Tetraphase, Jacques was CSO at Idenix (acquired by Merck in 2014) working on liver-targeted nucleosides and their applications in virology and oncology. From 2007 to 2014, Jacques worked at AstraZeneca, most recently as VP of Strategy, Infectious Diseases. Prior to that he spent 15 years at Bayer Healthcare. Jacques holds a Ph.D. in Organic Chemistry from Paris VI University and completed a Post-doctoral Fellowship at Stanford University. |
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Kaicheng |
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Zhu |
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Head of Operations, Boston |
Bellen |
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Kaicheng Zhu is the Director of Boston Operation at Bellen Chemistry. He is in charge of Business Development and Project Management of contract research and manufacturing. Kaicheng received his Ph.D. degree in organic chemistry at Boston University and did his postdoctoral research at the Scripps Research Institute (CA). Prior to joining Bellen, Kaicheng worked as a medicinal chemist at Pfizer Inc (Groton, CT) and process chemist at Enanta Pharmaceuticals (Watertown, MA). |
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Kevin |
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Kreutter |
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Vice President, Drug Discovery |
Empress Therapeutics |
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Kevin began his Drug Discovery career at 3DP, then Janssen, before moving to the Boston area. Formerly at Nimbus and now at a Flagship NewCo, he’s worked across therapeutic areas and is co-inventor of three clinical candidates, including the gut tissue-restricted pan-JAK inhibitor lorpucitinib. He’s currently VP of Drug Discovery at VL54 Toran + VL55 Empress and his team uses med chem, chemoproteomics, and synthetic biology to help develop novel therapeutics based on co-evolved, human-experienced molecules that play a privileged role in human health. |
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Liang |
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Mao |
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Senior Director, Head of Developability and Formulation Research |
WuXi AppTec |
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Liang Mao is currently a Senior Director at STA WuXi AppTec in Shanghai; he joined STA more than 6 years ago and now manages the developability and formulation research team. Prior to STA, Liang worked for around 6 years in Novartis’s pre-formulation team supporting compound developability assessment, physical form screening and selection, preclinical formulation development. He has another four years work experience in research institute and biopharmaceutical company supporting early drug development. He has expertise in drug developability assessment, physical form screening, and bioavailability enhancement technologies. Liang holds a master’s degree in bio-chemical engineering from Nanjing University of Technology. |
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Matthew |
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Lucas |
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VP of Medical Chemistry |
Third Harmonic Bio |
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Matt Lucas, with more than 20 years of drug discovery experience, is currently VP Chemistry at Third Harmonic Bio, a biopharmaceutical company focused on dermal, respiratory, and gastrointestinal inflammatory diseases. Recent roles also included serving as Chief Science Officer at Gandeeva Therapeutics, and SVP Drug Discovery at Black Diamond Therapeutics where he led the CNS-penetrant EGFR mutant inhibitor program that delivered BDTX-1535 to the clinic for the treatment of glioblastoma and NSCLC. Matt has also served in leadership roles at Yumanity Therapeutics, Cubist Pharmaceuticals and at Roche Pharmaceuticals, leading multiple projects across therapeutic areas including oncology, immunology and neuroscience. |
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Norman |
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Azoulay |
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Director – Scientific Products |
Excelra |
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Norman, a seasoned product leader with degrees in Neuroscience and Biology from Wesleyan University and Harvard University, respectively, leads Excelra’s scientific products team. He focuses on Excelra’s flagship platforms like GOSTAR and GOBIOM, aligning innovation with a user-centric approach. With diverse experience, including key roles at Elsevier and ADP, he has become a vital asset at Excelra. His expertise in data management plays a central role in drug discovery lead generation and optimization, ensuring that scientists across various fields consistently benefit from Excelra’s adaptive product offerings. |
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Onur |
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Atasoylu |
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Director, Head of Computational Chemistry |
Incyte |
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Onur Atasoylu obtained his Ph.D. from University of Pennsylvania in organic chemistry and undertook postdoctoral research at the University of Oxford, UK. He held various academic and industry positions in medicinal chemistry before joining Incyte Corporation in 2015. As the Head of Computational Chemistry at Incyte his research focuses on the design of small molecule inhibitors of targets in oncology and immunology. |
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Richard |
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Heidebrecht |
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Vice President of Research and Development |
Glycologix |
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Rich Heidebrecht is currently the Vice President of Research and Development at Glycologix. He started his career at Pfizer and Merck before making a transition to Biotech via the Broad Institute. Rich has gained expertise in medicinal, process and analytical chemistry and has worked on diverse therapeutic modalities such as small molecules, cell therapies, medical devices, and polymers including oligonucleotides. Over the course of his career, Rich has contributed to 35 patent/patent applications, 16 papers, two clinical programs and one marketed drug. Doctor Heidebrecht completed his undergraduate work at Worcester Polytechnic Institute and his graduate work at Indiana University with David R. Williams. His postdoc with Stephen Martin at the University of Texas at Austin rounded out two natural product synthesis projects – one total, one formal. |
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Robert |
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Goodnow |
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Head Drug Discovery Sciences |
Takeda |
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Robert Goodnow (Rob) is Head Drug Discovery Sciences at Takeda Pharmaceutical Company since August 2022; this group enables multiple therapeutic modalities. Rob began his industrial career at Roche, where his research focused on the implementation of multiple chemistry platform technologies. These include small molecule-targeted delivery of oligonucleotides for therapeutic application, analytical and computational chemistry as well as DNA-encoded chemistry. Rob’s efforts in medicinal chemistry have been focused on projects in oncology, inflammation, neurosciences, and metabolic diseases. He has authored or co-authored more than 90 scientific papers, book chapters and patent applications. In 2014, he published a book entitled “A Handbook of DNAEncoded Chemistry” (Wiley) |
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Sam |
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Baskaran |
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Director, Medicinal Chemistry |
WuXi AppTec |
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Dr. Sam Baskaran is Director, Medicinal Chemistry with the Research Chemistry Services/Integrated Program Management team at WuXi AppTec in Boston. He has over 20 years of drug discovery experience in the biotech and pharma industries (Novartis, Sunesis, GSK). He was trained as an organic chemist with a Ph.D. and PostDoc. Sam has an excellent track record of international publications, co-authored >50 publications, and >20 patents, and is one of the inventors of 5 clinical candidates. |
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Sejal |
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Patel |
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Vice President Chemistry |
Scorpion Therapeutics |
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Sejal is an entrepreneurial and data driven scientific leader who has two decades of drug discovery experience from concept to clinic. She is currently a Vice President of Chemistry at Scorpion Therapeutics, where she has been co-leading the early drug discovery portfolio, prioritizing and enabling novel targets using the company’s chemoproteomics, and covalent library platform towards lead optimization via integration of advanced technologies and scientific rigor. Prior to joining Scorpion, Sejal worked at Novartis Institute for Biomedical Research (NIBR) in global discovery chemistry where she led integrated drug discovery teams from early target validation to identification of clinical leads across multiple therapeutic areas, as well as supporting IND-enabling studies and filings. Sejal also has experience in portfolio strategy, delivery technologies, digital therapeutics, academic/biotech collaborations, and strategic partnerships. Sejal has been a long-standing advocate of mentorship programs to share experiences, and to level up inclusivity in the sciences. Sejal received her dual B.S. degrees in chemistry and biology from UC Irvine and her Ph.D. degree in organic chemistry from MIT under the supervision of Tim Jamison. |
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Shankar |
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Venkatraman |
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Executive Director, Chemistry |
IFM Therapeutics |
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Over his 20+ year industrial career Shankar Venkatraman has invented and progressed multiple compounds through discovery and into clinical development. He has focused on discovering first-in-class small molecule modulators of new biological pathways, closely integrating medicinal chemistry, pharmacology, and safety to enter clinical trials with these novel entities. Before joining IFM Therapeutics, LLC, Shankar was a Director of Chemistry at Vitae Pharmaceuticals. There he led number of programs including Menin-MLL, resulting in Revumenib (SNDX-5613), currently undergoing multiple clinical trials for ALL/AML with an anticipated NDA filing by the end of 2023. Prior to Vitae, he was a Senior Research Fellow at Merck, where he worked on number of modalities including HIV, neuropathic pain and schizophrenia, and delivered number of clinical candidates. Before joining Merck, Shankar began his medicinal chemistry career at Axys Pharmaceuticals, and worked on cathepsin K, with efforts leading to the identification of Odanacatib. Shankar obtained his Ph.D. in synthetic organic chemistry from University of Minnesota and B.S. in chemistry from University of Bombay. He is co-author/inventor on more than 60 papers and patents. |
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Sonela |
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Cavicke |
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Vice President of Discovery Business Development |
Sai Life Sciences Ltd |
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Since 2020, Sonela Cavicke is the West Coast VP of Business Development for Discovery Services at Sai Life Sciences. Sonela’s research background is in Immunology, particularly immunoassay development for vaccines, biologicals, and biomarkers. She completed her Bachelor’s and Master’s Degrees in Immunology and Microbiology at the University of Texas in Austin. She is a co-founder of a life sciences and diagnostic instrument company, Charted Scientific. She has held R&D positions at Luminex, Life Technologies, Merck Research Laboratories and Amgen and has worked in business development roles at MilliporeSigma, DiscoverX, and Eurofins Discovery prior to joining Sai. |
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Xiaoqi |
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(Charles) Chen |
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VP of Business Development |
Bellen Chemistry |
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Xiaoqi (Charles) Chen is VP of Business Development of Bellen Chemistry. He is working in business development and project management at Bellen. He helped Bellen establish the process optimization center in Shanghai. Before joining Bellen Chemistry, He worked at Amgen, Tularik, and Abbott Labs as a Principal Scientist engaging medicinal chemistry drug discovery. He obtained his PhD in organic chemistry at Rice University. |