Implementation of Machine Learning in Drug Development

Significant recent investment in computational technology has seen a number of new innovations arise in drug discovery - perhaps most notable machine learning (ML). By 2022, it is expected that AI technology will contribute $2.199 billion to pharma’s revenue, with...

4 years ago
Bioinformatics,AI & ML,Biology

Implementation of Machine Learning in Drug Development

Significant recent investment in computational technology has seen a number of new innovations arise in drug discovery - perhaps most notable machine learning (ML). By 2022, it is expected that AI technology will contribute $2.199 billion to pharma’s revenue, with...

4 years ago

-SAVED-Optimising The Manufacturing Process of Drug Development to Meet Demand

Over the last decade, biopharmaceutical manufacturing has needed to evolve rapidly to keep up with clinical demand for products. Innovations in recent years have seen production increase output quantities in a shorter period of time. Adaptations to production including single-use...

4 years ago
Bioprocess,Biomanufacturing,Biology,News

-SAVED-Optimising The Manufacturing Process of Drug Development to Meet Demand

Over the last decade, biopharmaceutical manufacturing has needed to evolve rapidly to keep up with clinical demand for products. Innovations in recent years have seen production increase output quantities in a shorter period of time. Adaptations to production including single-use...

4 years ago

Predicting Drug Toxicity: Challenges and Innovations

Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...

4 years ago
Pharmacovigilance,Biomanufacturing,Biology,News

Predicting Drug Toxicity: Challenges and Innovations

Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...

4 years ago

Real World Data and Evidence: Emerging Trends Across Clinical Research

Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...

4 years ago
Bioinformatics,Clinical Operations,Biology,News

Real World Data and Evidence: Emerging Trends Across Clinical Research

Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...

4 years ago

Strategies to Optimise Companion Diagnostics in Cancer

Companion diagnostic tests are an important part of precision medicine in oncology. In addition to matching optimal treatment options for patients, these tests enable clinicians to monitor the efficacy of therapeutic intervention in disease management. Innovations in cancer biopsies and...

4 years ago
Oncology,Precision and Personalised Medicine,AI & ML,Biology,News

Strategies to Optimise Companion Diagnostics in Cancer

Companion diagnostic tests are an important part of precision medicine in oncology. In addition to matching optimal treatment options for patients, these tests enable clinicians to monitor the efficacy of therapeutic intervention in disease management. Innovations in cancer biopsies and...

4 years ago

Phenotypic Screening in Early Drug Discovery: Opportunities and Challenges

Despite the prevalence of target-based discovery, phenotypic screening is emerging as a popular technique in early drug discovery. Challenges with target-based delivery have shown obvious flaws with predictive validity. The latest application of AI in phenotypic drug discovery has shown...

4 years ago
Precision and Personalised Medicine,Biology,News

Phenotypic Screening in Early Drug Discovery: Opportunities and Challenges

Despite the prevalence of target-based discovery, phenotypic screening is emerging as a popular technique in early drug discovery. Challenges with target-based delivery have shown obvious flaws with predictive validity. The latest application of AI in phenotypic drug discovery has shown...

4 years ago

Precision Medicine in Oncology: A Comparative Evaluation of SMDCs and ADCs

Targeted therapy - a treatment targeting proteins responsible for cancer growth - is one of the latest developments in precision oncology. The variable response of cancer treatments highlights the need to develop therapies that can target the specific profile of...

4 years ago
Oncology,Clinical Operations,Biology,News

Precision Medicine in Oncology: A Comparative Evaluation of SMDCs and ADCs

Targeted therapy - a treatment targeting proteins responsible for cancer growth - is one of the latest developments in precision oncology. The variable response of cancer treatments highlights the need to develop therapies that can target the specific profile of...

4 years ago

Disease Models and Target Validation: An Interview with Professor Gavin Woodhall

In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...

4 years ago
R&D,Biology,News

Disease Models and Target Validation: An Interview with Professor Gavin Woodhall

In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...

4 years ago

An Evaluation of Data Capture and Visualization in Clinical Research

Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...

4 years ago
Bioinformatics,Biology,News

An Evaluation of Data Capture and Visualization in Clinical Research

Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...

4 years ago

Challenges of Modelling Human Disease – Optimising Target Validation

The complexity of the human body presents a challenge when choosing a model that is translatable and can also be manipulated for target validation. In addition to the popular animal models, recent innovations in computational biology has seen significant advancements...

4 years ago
R&D,Biology

Challenges of Modelling Human Disease – Optimising Target Validation

The complexity of the human body presents a challenge when choosing a model that is translatable and can also be manipulated for target validation. In addition to the popular animal models, recent innovations in computational biology has seen significant advancements...

4 years ago