Preclinical Pharmacokinetics: Solving the Problems of Early-Stage Predictive Assays

Understanding the pharmacokinetic profile (PK) of a compound is critical in selecting appropriate drug candidates in preclinical studies. The challenge is to predict the PKs of compounds in humans using early-stage predictive assays in these studies. Innovations in the last...

22 hours ago
Biology,News

Preclinical Pharmacokinetics: Solving the Problems of Early-Stage Predictive Assays

Understanding the pharmacokinetic profile (PK) of a compound is critical in selecting appropriate drug candidates in preclinical studies. The challenge is to predict the PKs of compounds in humans using early-stage predictive assays in these studies. Innovations in the last...

22 hours ago

Emerging therapeutic areas of clinical attention & investment opportunities

Investment opportunities have changed substantially across the life sciences and pharmaceutical industry in the last ten years. It has become obvious that areas like neuroscience and respiratory medicine require additional support due to unmet clinical needs. Investment is key to...

4 days ago
Clinical Development,Biology,News

Emerging therapeutic areas of clinical attention & investment opportunities

Investment opportunities have changed substantially across the life sciences and pharmaceutical industry in the last ten years. It has become obvious that areas like neuroscience and respiratory medicine require additional support due to unmet clinical needs. Investment is key to...

4 days ago

Weekly News Round-up – 16/4/21

In the news this week, Johnson & Johnson’s (J&J’s) COVID-19 vaccine rollout in Europe halted following blood clot concerns in the U.S. In other news, a biopharma partnership aims to expedite drug development in immunology, and research reveals substantial public...

4 days ago
Weekly Roundups,Biology,News

Weekly News Round-up – 16/4/21

In the news this week, Johnson & Johnson’s (J&J’s) COVID-19 vaccine rollout in Europe halted following blood clot concerns in the U.S. In other news, a biopharma partnership aims to expedite drug development in immunology, and research reveals substantial public...

4 days ago

Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls

Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...

7 days ago
R&D,Biology

Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls

Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...

7 days ago

Weekly News Round-up – 9/4/21

In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug.  GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...

2 weeks ago
R&D,Clinical Development,Weekly Roundups,Biology

Weekly News Round-up – 9/4/21

In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug.  GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...

2 weeks ago

Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

2 weeks ago
Clinical Development,Clinical Operations,Biology

Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

2 weeks ago

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

2 weeks ago
R&D,Clinical Development,Biology

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

2 weeks ago

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

2 weeks ago
Oncology,R&D,Clinical Development,Biology,News

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

2 weeks ago

Immunotherapy and biomarkers: Developments in Combination Therapy for Cancer

Immunotherapy and Biomarkers: Developments in Combination Therapy for Cancer  Over the past few years, increasing evidence has supported the role of biomarkers in immunotherapy. Combination therapy - the use of a combination of products or modalities to treat cancer -...

2 weeks ago
Oncology,R&D,Clinical Development,Biology

Immunotherapy and biomarkers: Developments in Combination Therapy for Cancer

Immunotherapy and Biomarkers: Developments in Combination Therapy for Cancer  Over the past few years, increasing evidence has supported the role of biomarkers in immunotherapy. Combination therapy - the use of a combination of products or modalities to treat cancer -...

2 weeks ago

Weekly News Round-up – 1/4/21

In the news this week, GSK agrees to support NOVAVAX vaccine production to meet UK targets. In other news, Amgen Inc. confirms its agreement to acquire Rodeo Therapeutics, and COVID-19 vaccine production is boosted by expansions in production with BioNtech...

3 weeks ago
R&D,Biomanufacturing,Clinical Operations,Weekly Roundups,Biology

Weekly News Round-up – 1/4/21

In the news this week, GSK agrees to support NOVAVAX vaccine production to meet UK targets. In other news, Amgen Inc. confirms its agreement to acquire Rodeo Therapeutics, and COVID-19 vaccine production is boosted by expansions in production with BioNtech...

3 weeks ago