Intrinsically Disordered Proteins – The Implication in Cancer and Potential Drug Targets

Intrinsically disordered proteins (IDPs) are under the limelight in cancer research. While research is continuous in understanding their dynamic structure, their implication in tumour development is becoming increasingly evident. Some of the latest advancements demonstrate how IDPs can be used...

4 months ago
Oncology,R&D

Intrinsically Disordered Proteins – The Implication in Cancer and Potential Drug Targets

Intrinsically disordered proteins (IDPs) are under the limelight in cancer research. While research is continuous in understanding their dynamic structure, their implication in tumour development is becoming increasingly evident. Some of the latest advancements demonstrate how IDPs can be used...

4 months ago

The Latest Advancements in Immuno-oncology: Checkpoint Inhibitors

Until now, patients with advanced cervical cancer had relatively low survival rates. The recent approval of Keytruda, a PD-1/PD-L1 checkpoint inhibitor, is the latest breakthrough for cervical cancer immunotherapy. The positive outcome from Merck & Co’s clinical trial now offers...

5 months ago
Oncology,Biology,News

The Latest Advancements in Immuno-oncology: Checkpoint Inhibitors

Until now, patients with advanced cervical cancer had relatively low survival rates. The recent approval of Keytruda, a PD-1/PD-L1 checkpoint inhibitor, is the latest breakthrough for cervical cancer immunotherapy. The positive outcome from Merck & Co’s clinical trial now offers...

5 months ago

Protein-Based Diagnostic Biomarkers for Cancer: Where Are We Now?

While significant progression has been made in cancer therapeutics, the disease remains a serious health risk. The lack of commercially available diagnostic biomarkers hinders accurate early cancer diagnosis which could otherwise save many lives. Protein-based biomarkers have demonstrated the potential...

6 months ago
Oncology,Precision and Personalised Medicine

Protein-Based Diagnostic Biomarkers for Cancer: Where Are We Now?

While significant progression has been made in cancer therapeutics, the disease remains a serious health risk. The lack of commercially available diagnostic biomarkers hinders accurate early cancer diagnosis which could otherwise save many lives. Protein-based biomarkers have demonstrated the potential...

6 months ago

Aseptic Processing: Maintaining Sterility in Pharmaceutical Manufacturing

In 2019, drug manufacturer Genzyme was thought to have lost up to $300m in revenue due to plant shutdown after product contamination. Ensuring appropriate aseptic practices are followed can mean the difference between efficient manufacturing operations and the shutting down...

6 months ago
Oncology,Biomanufacturing

Aseptic Processing: Maintaining Sterility in Pharmaceutical Manufacturing

In 2019, drug manufacturer Genzyme was thought to have lost up to $300m in revenue due to plant shutdown after product contamination. Ensuring appropriate aseptic practices are followed can mean the difference between efficient manufacturing operations and the shutting down...

6 months ago

Another Direction for Clinical Oncology: Targeting the Anti-Inflammatory Response in Cancer

Approximately 15-20% of all cancer cases are preceded by infection, chronic inflammation, or autoimmunity at the same tissue or organ site. While inflammation is a natural response to tissue damage, chronic inflammation can become pathological. The role of inflammation in...

6 months ago
Oncology,Biology,News

Another Direction for Clinical Oncology: Targeting the Anti-Inflammatory Response in Cancer

Approximately 15-20% of all cancer cases are preceded by infection, chronic inflammation, or autoimmunity at the same tissue or organ site. While inflammation is a natural response to tissue damage, chronic inflammation can become pathological. The role of inflammation in...

6 months ago

How Has The Covid-19 Pandemic Impacted Oncology and Clinical Operations?

As a part of Proventa’s Clinical Operations and Oncology Meeting May 2021, we organised a number of interesting keynote sessions pondering the latest innovations, challenges and strategies for the future. The morning keynote, hosted by Tanya Russel Kirkpatrick, VP Clinical...

6 months ago
Oncology,Clinical Operations,Biology,News

How Has The Covid-19 Pandemic Impacted Oncology and Clinical Operations?

As a part of Proventa’s Clinical Operations and Oncology Meeting May 2021, we organised a number of interesting keynote sessions pondering the latest innovations, challenges and strategies for the future. The morning keynote, hosted by Tanya Russel Kirkpatrick, VP Clinical...

6 months ago

Biomarker Discovery and Validation: Current Challenges in Oncology

Biomarkers have shown significant potential across oncology clinical studies, especially in precision medicine for immunotherapy. Therefore, it is important that biomarker discovery and validation is optimised to produce the most effective drugs for patient populations. False positives and experimental bias...

6 months ago
Oncology,R&D,Biology,News

Biomarker Discovery and Validation: Current Challenges in Oncology

Biomarkers have shown significant potential across oncology clinical studies, especially in precision medicine for immunotherapy. Therefore, it is important that biomarker discovery and validation is optimised to produce the most effective drugs for patient populations. False positives and experimental bias...

6 months ago

The Latest Developments in Precision Oncology

Precision medicine is a rapidly growing therapeutic area within oncology. Technological innovations have contributed to the refinement of predictive and diagnostic techniques used to tailor therapy for cancer patients. The goal is to not only develop more precise treatments, but...

7 months ago
Oncology,Precision and Personalised Medicine,AI & ML,Biology,News

The Latest Developments in Precision Oncology

Precision medicine is a rapidly growing therapeutic area within oncology. Technological innovations have contributed to the refinement of predictive and diagnostic techniques used to tailor therapy for cancer patients. The goal is to not only develop more precise treatments, but...

7 months ago

An Evaluation of -Omics Technology

Omics technologies have proven to be useful molecular tools across many therapeutic areas in facilitating qualitative and quantitative tissue analysis. Spatially Resolved Transcriptomics (SRT) is an example of -omics technology used in oncology to further investigate how the heterogeneity of...

7 months ago
Oncology,Bioinformatics,Biology

An Evaluation of -Omics Technology

Omics technologies have proven to be useful molecular tools across many therapeutic areas in facilitating qualitative and quantitative tissue analysis. Spatially Resolved Transcriptomics (SRT) is an example of -omics technology used in oncology to further investigate how the heterogeneity of...

7 months ago

Future Trends for Pharma and Life Sciences 2021

Given the considerable seismic shifts occurring in the pharmaceutical and life sciences sectors recently, it is no surprise that the major trends and investments of 2021 have seen a similar change in focus. Alzheimer’s Disease, genome editing and cellular therapy...

7 months ago
Oncology,R&D,CGT,Precision and Personalised Medicine,Biology,News

Future Trends for Pharma and Life Sciences 2021

Given the considerable seismic shifts occurring in the pharmaceutical and life sciences sectors recently, it is no surprise that the major trends and investments of 2021 have seen a similar change in focus. Alzheimer’s Disease, genome editing and cellular therapy...

7 months ago