RNA Therapeutics: Innovations in Disease Research and Drug Development

RNA has proven in the last decade to be a valid therapeutic target for a multitude of diseases. The ability to manipulate the genetic code to produce almost any protein is one of the many advantages that has also led...

3 weeks ago
R&D,Biology

RNA Therapeutics: Innovations in Disease Research and Drug Development

RNA has proven in the last decade to be a valid therapeutic target for a multitude of diseases. The ability to manipulate the genetic code to produce almost any protein is one of the many advantages that has also led...

3 weeks ago

Emerging Innovations in Translational Medicine: An Interview with Marcie Glicksman, Enclear Therapies

3D cultures and organ-on-a-chip are a few examples of technologies that hope to bridge the gap from benchside to clinic. Failures that arise during drug development often arise due to poor translatability from models in preclinical studies to the patients...

3 weeks ago
R&D,Biology

Emerging Innovations in Translational Medicine: An Interview with Marcie Glicksman, Enclear Therapies

3D cultures and organ-on-a-chip are a few examples of technologies that hope to bridge the gap from benchside to clinic. Failures that arise during drug development often arise due to poor translatability from models in preclinical studies to the patients...

3 weeks ago

Drugs in Space: How Extraterrestrial Experiments Help Us Develop Medicine

Over the last 20 years, fundamental scientific research has been conducted by astronauts aboard the international space station (ISS). It has only been recently that the pharmaceutical and biotech sectors have invested in extraterrestrial experiments, hoping to find novel ways...

3 weeks ago
R&D,Biology

Drugs in Space: How Extraterrestrial Experiments Help Us Develop Medicine

Over the last 20 years, fundamental scientific research has been conducted by astronauts aboard the international space station (ISS). It has only been recently that the pharmaceutical and biotech sectors have invested in extraterrestrial experiments, hoping to find novel ways...

3 weeks ago

Vaccines and Variants: How Do They Work?

As of 23 June 2021, there are 14 variants of COVID-19 which are of concern or under investigation in the UK, according to the UK government. The unique profile of COVID-19 enables rapid mutation, producing variants which are more transmissible...

1 month ago
R&D,Biology,News

Vaccines and Variants: How Do They Work?

As of 23 June 2021, there are 14 variants of COVID-19 which are of concern or under investigation in the UK, according to the UK government. The unique profile of COVID-19 enables rapid mutation, producing variants which are more transmissible...

1 month ago

Building a FAIR Culture in Pharma

The development of a ‘Findable, Accessible, Interoperable and Reusable’ (FAIR) data approach has been an exciting step towards an information-centric approach for the pharmaceutical industry. The potential benefits of this alternative approach to data management and accessibility could significantly support...

1 month ago
R&D,Bioinformatics,Data,News

Building a FAIR Culture in Pharma

The development of a ‘Findable, Accessible, Interoperable and Reusable’ (FAIR) data approach has been an exciting step towards an information-centric approach for the pharmaceutical industry. The potential benefits of this alternative approach to data management and accessibility could significantly support...

1 month ago

Utilising Machine Learning in Drug Discovery: Opportunities and Challenges

From artificial neural networks to predictive modelling, artificial intelligence (AI) is making its mark in the pharmaceutical industry. The ever-increasing cost of development, shorter timelines and rise in demand has seen the industry reach out to AI to help bring...

1 month ago
R&D,AI & ML,News

Utilising Machine Learning in Drug Discovery: Opportunities and Challenges

From artificial neural networks to predictive modelling, artificial intelligence (AI) is making its mark in the pharmaceutical industry. The ever-increasing cost of development, shorter timelines and rise in demand has seen the industry reach out to AI to help bring...

1 month ago

The Potential of Therapeutic Psychedelics Drugs: An Interview with Professor Albert Garcia-Romeu

Mental health conditions like addiction and diseases like Alzheimer’s represent a great unmet clinical need. Psychedelic research at preclinical stages have shown potential for positive neurological changes in the brain for models of depression, addiction and Alzheimer's. In a recent...

1 month ago
R&D,Precision and Personalised Medicine,Biology,News

The Potential of Therapeutic Psychedelics Drugs: An Interview with Professor Albert Garcia-Romeu

Mental health conditions like addiction and diseases like Alzheimer’s represent a great unmet clinical need. Psychedelic research at preclinical stages have shown potential for positive neurological changes in the brain for models of depression, addiction and Alzheimer's. In a recent...

1 month ago

Strategies Implemented for New Modalities of Therapeutic Targeting: ASOs and RNAi

In 2018, the FDA approved the first small interfering RNA (siRNA) drug, patisiran, to treat a disease known as hereditary transthyretin amyloidosis. Since then, an increasing number of oligonucleotide-based drugs have reached the market, showing advantages over small molecule drugs....

1 month ago
R&D,Bioprocess,Biology,News

Strategies Implemented for New Modalities of Therapeutic Targeting: ASOs and RNAi

In 2018, the FDA approved the first small interfering RNA (siRNA) drug, patisiran, to treat a disease known as hereditary transthyretin amyloidosis. Since then, an increasing number of oligonucleotide-based drugs have reached the market, showing advantages over small molecule drugs....

1 month ago

Using Translational Research to Bridge the Gap Between Preclinical and Clinical Research

The disparity between animal models and clinical efficacy is compromising the safety and efficacy of therapeutic drugs. Translational research is building the bridge between preclinical studies and therapeutic treatment. Genomic techniques and non-traditional animal models are examples of translational approaches...

2 months ago
R&D,Clinical Development,Clinical Operations,Biology,News

Using Translational Research to Bridge the Gap Between Preclinical and Clinical Research

The disparity between animal models and clinical efficacy is compromising the safety and efficacy of therapeutic drugs. Translational research is building the bridge between preclinical studies and therapeutic treatment. Genomic techniques and non-traditional animal models are examples of translational approaches...

2 months ago

Moving Towards Phenotypic Screening in Drug Discovery: An Interview with Prasun Mishra

Despite the technological advances, drug discovery is still a lengthy, expensive, and difficult stage in the drug development process. Screening assays are a critical part of rapidly and thoroughly analysing vast numbers of compounds for desired biochemical activity. In a...

2 months ago
R&D,Biology,News

Moving Towards Phenotypic Screening in Drug Discovery: An Interview with Prasun Mishra

Despite the technological advances, drug discovery is still a lengthy, expensive, and difficult stage in the drug development process. Screening assays are a critical part of rapidly and thoroughly analysing vast numbers of compounds for desired biochemical activity. In a...

2 months ago