The Clinical Challenges of Rare Disease Research: An Interview with Dr. Evangeline Wassmer
In a recent interview with Dr. Evangeline Wassmer, Paediatric neurology consultant at Birmingham Children’s Hospital, Proventa discussed the problems with rare disease clinical research. Dr. Wassmer has extensive experience in paedatric rare diseases - paediatric Multiple Sclerosis, neurometabolic and neurodegenerative...
4 years agoThe Clinical Challenges of Rare Disease Research: An Interview with Dr. Evangeline Wassmer
In a recent interview with Dr. Evangeline Wassmer, Paediatric neurology consultant at Birmingham Children’s Hospital, Proventa discussed the problems with rare disease clinical research. Dr. Wassmer has extensive experience in paedatric rare diseases - paediatric Multiple Sclerosis, neurometabolic and neurodegenerative...
4 years ago
Optimising Screening Strategies and Early Detection of Cancer: A Challenge for Pharma and Clinical Industries
Screening methods in oncology are critical to enable doctors to detect cancer in at-risk populations. Early detection of the disease is essential to choose appropriate treatment to increase the chance of survival. The latest research identifies flaws in clinical screening...
4 years agoOptimising Screening Strategies and Early Detection of Cancer: A Challenge for Pharma and Clinical Industries
Screening methods in oncology are critical to enable doctors to detect cancer in at-risk populations. Early detection of the disease is essential to choose appropriate treatment to increase the chance of survival. The latest research identifies flaws in clinical screening...
4 years ago
Innovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years agoInnovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years ago
Preclinical Pharmacokinetics: Solving the Problems of Early-Stage Predictive Assays
Understanding the pharmacokinetic profile (PK) of a compound is critical in selecting appropriate drug candidates in preclinical studies. The challenge is to predict the PKs of compounds in humans using early-stage predictive assays in these studies. Innovations in the last...
4 years agoPreclinical Pharmacokinetics: Solving the Problems of Early-Stage Predictive Assays
Understanding the pharmacokinetic profile (PK) of a compound is critical in selecting appropriate drug candidates in preclinical studies. The challenge is to predict the PKs of compounds in humans using early-stage predictive assays in these studies. Innovations in the last...
4 years ago
Emerging therapeutic areas of clinical attention & investment opportunities
Investment opportunities have changed substantially across the life sciences and pharmaceutical industry in the last ten years. It has become obvious that areas like neuroscience and respiratory medicine require additional support due to unmet clinical needs. Investment is key to...
4 years agoEmerging therapeutic areas of clinical attention & investment opportunities
Investment opportunities have changed substantially across the life sciences and pharmaceutical industry in the last ten years. It has become obvious that areas like neuroscience and respiratory medicine require additional support due to unmet clinical needs. Investment is key to...
4 years ago
Weekly News Round-up – 16/4/21
In the news this week, Johnson & Johnson’s (J&J’s) COVID-19 vaccine rollout in Europe halted following blood clot concerns in the U.S. In other news, a biopharma partnership aims to expedite drug development in immunology, and research reveals substantial public...
4 years agoWeekly News Round-up – 16/4/21
In the news this week, Johnson & Johnson’s (J&J’s) COVID-19 vaccine rollout in Europe halted following blood clot concerns in the U.S. In other news, a biopharma partnership aims to expedite drug development in immunology, and research reveals substantial public...
4 years ago
Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years agoDiscovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years ago
Weekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years agoWeekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years ago
Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry
Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...
4 years agoPredicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry
Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...
4 years ago
A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years agoA Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years ago