Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

4 years ago
Clinical Development,Clinical Operations,Biology

Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

4 years ago

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

4 years ago
R&D,Clinical Development,Biology

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

4 years ago

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

4 years ago
Oncology,R&D,Clinical Development,Biology,News

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

4 years ago

Evolving Drug Delivery in Parkinson’s Clinical Trials

Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...

4 years ago
Clinical Development,Biology,News

Evolving Drug Delivery in Parkinson’s Clinical Trials

Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...

4 years ago

Immunotherapy and biomarkers: Developments in Combination Therapy for Cancer

Over the past few years, increasing evidence has supported the role of biomarkers in immunotherapy. Combination therapy - the use of a combination of products or modalities to treat cancer - is one way to use biomarkers to reveal the...

4 years ago
Oncology,R&D,Clinical Development,Biology

Immunotherapy and biomarkers: Developments in Combination Therapy for Cancer

Over the past few years, increasing evidence has supported the role of biomarkers in immunotherapy. Combination therapy - the use of a combination of products or modalities to treat cancer - is one way to use biomarkers to reveal the...

4 years ago

Weekly News Round-up – 1/4/21

In the news this week, GSK agrees to support NOVAVAX vaccine production to meet UK targets. In other news, Amgen Inc. confirms its agreement to acquire Rodeo Therapeutics, and COVID-19 vaccine production is boosted by expansions in production with BioNtech...

4 years ago
R&D,Biomanufacturing,Clinical Operations,Weekly Roundups,Biology

Weekly News Round-up – 1/4/21

In the news this week, GSK agrees to support NOVAVAX vaccine production to meet UK targets. In other news, Amgen Inc. confirms its agreement to acquire Rodeo Therapeutics, and COVID-19 vaccine production is boosted by expansions in production with BioNtech...

4 years ago

The Challenges of Drug Delivery: An Interview With Prof. Afzal R Mohammed

Conventional drug delivery methods, such as oral and systemic administration, face issues of optimisation, and present certain challenges for physicians. Proventa spoke to Professor Afzal Ur-Rahman Mohammed, Head of Pharmaceutical Sciences at Aston University Pharmacy School, about these challenges, and...

4 years ago
R&D,Clinical Development,News

The Challenges of Drug Delivery: An Interview With Prof. Afzal R Mohammed

Conventional drug delivery methods, such as oral and systemic administration, face issues of optimisation, and present certain challenges for physicians. Proventa spoke to Professor Afzal Ur-Rahman Mohammed, Head of Pharmaceutical Sciences at Aston University Pharmacy School, about these challenges, and...

4 years ago

Weekly News Round-Up – 26/3/21

In the news this week, reports urge pharmaceutical companies to exploit the benefits of synthetic data in clinical trials. In other news, FDA fears over the safety of tanezumab compromises approval for the Pfizer/Lilly pain drug, and the COSMIC database...

4 years ago
R&D,Bioprocess,Clinical Development,Weekly Roundups,Biology

Weekly News Round-Up – 26/3/21

In the news this week, reports urge pharmaceutical companies to exploit the benefits of synthetic data in clinical trials. In other news, FDA fears over the safety of tanezumab compromises approval for the Pfizer/Lilly pain drug, and the COSMIC database...

4 years ago

Optimising Paediatric Studies in Clinical Drug Development

Drug development in the world of paediatric medicine is hitting a wall. Without developing new strategies, patient recruitment and retention will continue to plummet and jeopardise lives. Innovative changes to clinical trial design and learning about patient incentives have opened...

4 years ago
Clinical Development,Clinical Operations,News

Optimising Paediatric Studies in Clinical Drug Development

Drug development in the world of paediatric medicine is hitting a wall. Without developing new strategies, patient recruitment and retention will continue to plummet and jeopardise lives. Innovative changes to clinical trial design and learning about patient incentives have opened...

4 years ago

Plant-Derived Vaccines Versus COVID-19

Despite success with the COVID-19 vaccine roll-out, ever-increasing demand across the world continues to put pressure on vaccine manufacturing and supply chains. Recent developments in plant-derived vaccines, however, offer a potential solution. GSK is one company currently implementing phase III...

4 years ago
R&D,Biomanufacturing,Clinical Development,News

Plant-Derived Vaccines Versus COVID-19

Despite success with the COVID-19 vaccine roll-out, ever-increasing demand across the world continues to put pressure on vaccine manufacturing and supply chains. Recent developments in plant-derived vaccines, however, offer a potential solution. GSK is one company currently implementing phase III...

4 years ago