Predicting Drug Toxicity: Challenges and Innovations
Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...
4 years agoPredicting Drug Toxicity: Challenges and Innovations
Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...
4 years ago
Real World Data and Evidence: Emerging Trends Across Clinical Research
Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...
4 years agoReal World Data and Evidence: Emerging Trends Across Clinical Research
Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...
4 years ago
Strategies to Optimise Companion Diagnostics in Cancer
Companion diagnostic tests are an important part of precision medicine in oncology. In addition to matching optimal treatment options for patients, these tests enable clinicians to monitor the efficacy of therapeutic intervention in disease management. Innovations in cancer biopsies and...
4 years agoStrategies to Optimise Companion Diagnostics in Cancer
Companion diagnostic tests are an important part of precision medicine in oncology. In addition to matching optimal treatment options for patients, these tests enable clinicians to monitor the efficacy of therapeutic intervention in disease management. Innovations in cancer biopsies and...
4 years ago
Phenotypic Screening in Early Drug Discovery: Opportunities and Challenges
Despite the prevalence of target-based discovery, phenotypic screening is emerging as a popular technique in early drug discovery. Challenges with target-based delivery have shown obvious flaws with predictive validity. The latest application of AI in phenotypic drug discovery has shown...
4 years agoPhenotypic Screening in Early Drug Discovery: Opportunities and Challenges
Despite the prevalence of target-based discovery, phenotypic screening is emerging as a popular technique in early drug discovery. Challenges with target-based delivery have shown obvious flaws with predictive validity. The latest application of AI in phenotypic drug discovery has shown...
4 years ago
Precision Medicine in Oncology: A Comparative Evaluation of SMDCs and ADCs
Targeted therapy - a treatment targeting proteins responsible for cancer growth - is one of the latest developments in precision oncology. The variable response of cancer treatments highlights the need to develop therapies that can target the specific profile of...
4 years agoPrecision Medicine in Oncology: A Comparative Evaluation of SMDCs and ADCs
Targeted therapy - a treatment targeting proteins responsible for cancer growth - is one of the latest developments in precision oncology. The variable response of cancer treatments highlights the need to develop therapies that can target the specific profile of...
4 years ago
Disease Models and Target Validation: An Interview with Professor Gavin Woodhall
In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...
4 years agoDisease Models and Target Validation: An Interview with Professor Gavin Woodhall
In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...
4 years ago
An Evaluation of Data Capture and Visualization in Clinical Research
Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...
4 years agoAn Evaluation of Data Capture and Visualization in Clinical Research
Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...
4 years ago
The Clinical Challenges of Rare Disease Research: An Interview with Dr. Evangeline Wassmer
In a recent interview with Dr. Evangeline Wassmer, Paediatric neurology consultant at Birmingham Children’s Hospital, Proventa discussed the problems with rare disease clinical research. Dr. Wassmer has extensive experience in paedatric rare diseases - paediatric Multiple Sclerosis, neurometabolic and neurodegenerative...
4 years agoThe Clinical Challenges of Rare Disease Research: An Interview with Dr. Evangeline Wassmer
In a recent interview with Dr. Evangeline Wassmer, Paediatric neurology consultant at Birmingham Children’s Hospital, Proventa discussed the problems with rare disease clinical research. Dr. Wassmer has extensive experience in paedatric rare diseases - paediatric Multiple Sclerosis, neurometabolic and neurodegenerative...
4 years ago
Optimising Screening Strategies and Early Detection of Cancer: A Challenge for Pharma and Clinical Industries
Screening methods in oncology are critical to enable doctors to detect cancer in at-risk populations. Early detection of the disease is essential to choose appropriate treatment to increase the chance of survival. The latest research identifies flaws in clinical screening...
4 years agoOptimising Screening Strategies and Early Detection of Cancer: A Challenge for Pharma and Clinical Industries
Screening methods in oncology are critical to enable doctors to detect cancer in at-risk populations. Early detection of the disease is essential to choose appropriate treatment to increase the chance of survival. The latest research identifies flaws in clinical screening...
4 years ago
Innovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years agoInnovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years ago