Predicting Drug Toxicity: Challenges and Innovations
Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...
4 years agoPredicting Drug Toxicity: Challenges and Innovations
Failure to reach the desired safety profile is one of the main reasons for delayed drug development. Advancements in preclinical studies have seen the optimisation of in vitro assays to better predict toxicity in drug discovery. Computational methods like in...
4 years ago
Real World Data and Evidence: Emerging Trends Across Clinical Research
Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...
4 years agoReal World Data and Evidence: Emerging Trends Across Clinical Research
Real-world data (RWD) and real-word evidence (RWE) are increasingly used to support drug development and clinical research across life sciences. RWE studies provide insight into the implementation of therapeutic drugs clinical practice based on RWD of the patient population. RWD...
4 years ago
Disease Models and Target Validation: An Interview with Professor Gavin Woodhall
In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...
4 years agoDisease Models and Target Validation: An Interview with Professor Gavin Woodhall
In a recent interview with Proventa, Professor Gavin Woodhall, research scientist and Head of Neuroscience at Aston University, discussed the challenges of modelling human disease and the impact of alternative models on target validation. Professor Woodhall has an extensive academic...
4 years ago
An Evaluation of Data Capture and Visualization in Clinical Research
Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...
4 years agoAn Evaluation of Data Capture and Visualization in Clinical Research
Data capture and visualization are the key components of clinical trial data analysis. However, with the explosion of COVID-19 around the world, data collection became difficult with poor patient recruitment and a reduction in face-to-face clinics. Advancements in telehealth have...
4 years ago
Challenges of Modelling Human Disease – Optimising Target Validation
The complexity of the human body presents a challenge when choosing a model that is translatable and can also be manipulated for target validation. In addition to the popular animal models, recent innovations in computational biology has seen significant advancements...
4 years agoChallenges of Modelling Human Disease – Optimising Target Validation
The complexity of the human body presents a challenge when choosing a model that is translatable and can also be manipulated for target validation. In addition to the popular animal models, recent innovations in computational biology has seen significant advancements...
4 years ago
Innovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years agoInnovations addressing the challenges of oncology clinical research to treat rare and ultra-rare diseases
Rare cancers are notoriously difficult to study and present a critical problem in clinical research. Innovations to clinical trial design and patient recruitment are some of the many changes in the field to optimise the outcome of clinical trials for...
4 years ago
Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years agoDiscovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years ago
Weekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years agoWeekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years ago
A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years agoA Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years ago
Innovations in Oncology Today: An Interview with Jessicca Rege
Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...
4 years agoInnovations in Oncology Today: An Interview with Jessicca Rege
Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...
4 years ago