Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls

Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...

4 years ago
R&D,Biology

Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls

Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...

4 years ago

Weekly News Round-up – 9/4/21

In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug.  GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...

4 years ago
R&D,Clinical Development,Weekly Roundups,Biology

Weekly News Round-up – 9/4/21

In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug.  GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...

4 years ago

Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

4 years ago
Clinical Development,Clinical Operations,Biology

Predicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry

Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...

4 years ago

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

4 years ago
R&D,Clinical Development,Biology

A Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research

In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...

4 years ago

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

4 years ago
Oncology,R&D,Clinical Development,Biology,News

Innovations in Oncology Today: An Interview with Jessicca Rege

Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...

4 years ago

Evolving Drug Delivery in Parkinson’s Clinical Trials

Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...

4 years ago
Clinical Development,Biology,News

Evolving Drug Delivery in Parkinson’s Clinical Trials

Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...

4 years ago
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