Discovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years agoDiscovering Novel Chemical Entities with DNA-Encoded Libraries: Promises and Pitfalls
Early drug discovery in the pharmaceutical industry has driven the development of technology to create large libraries of compounds for screening of chemical targets. Innovations in DNA-encoded libraries have been critical in optimising drug discovery, demonstrating greater selectivity of hit...
4 years agoWeekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years agoWeekly News Round-up – 9/4/21
In the news this week, Genmab suggests potential investment plans for spin-off biotechs. In other news, alternative COVID-19 vaccines offered to under-30s, and Acadia fails to achieve FDA approval for psychosis drug. GENMAB CEO HINTS AT FUTURE INVESTMENT PLANS –...
4 years agoPredicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry
Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...
4 years agoPredicting and Improving Clinical Trial Enrolment: A Problem for Psychiatry
Patient enrolment is a common issue across many therapeutic areas in clinical research. Psychiatric disorders in particular represent a trial area with significantly high drop-out rates and poor patient recruitment. The reasons behind this problem, however, are rarely studied or...
4 years agoA Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years agoA Critical Evaluation of the Advantages and Limitations of In Silico Methods in Clinical Research
In silico models - simulations of a complex system in the form of equations or rules - are becoming increasingly popular in the drug development process and across clinical research. Use of computational models and simulations offers significant advantages over...
4 years agoInnovations in Oncology Today: An Interview with Jessicca Rege
Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...
4 years agoInnovations in Oncology Today: An Interview with Jessicca Rege
Even aside from the COVID-19 pandemic, 2020 saw a number of innovations in the oncology space, from novel cytokine development to use of NGS to further patient-centric treatment. We spoke to Jessicca Rege, Vice President and Head of Oncology at...
4 years agoEvolving Drug Delivery in Parkinson’s Clinical Trials
Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...
4 years agoEvolving Drug Delivery in Parkinson’s Clinical Trials
Effective drug delivery represents a significant challenge in the clinical trial setting, especially for neurological disorders like Parkinson’s. Over the last decade, Parkinson's clinical trials have slowly tried to implement systems to deliver the appropriate therapeutic dose of drugs to...
4 years ago